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Principal Clinical Trials Bioscanner® TRIMprob™ with pubblications

 

Organ

N° patients

Sensibility
%

Specificity
%

Positive Predictive Value (P.P.V)

Negative Predictive Value (N.P.V.)

Accuracy
%

SCIENTIFIC ARTICLE

PROSTATE

             

1- Prof. Scialpi M, Prof. Vedruccio C.
(HSS Annunziata Taranto)

43

94

92

 

96

93

Nuove possibilità diagnostiche tramite onde elettromagnetiche (Fisica in medicina 2004)

 

 

2 – Dr. Bellorofonte C et Al.
(HSCarlo – Milano)

757

95

43

94

90

 

Non-invasive detection of prostate cancer by electromagnetic interaction
(European Urology, Jan. 2005)

 

 

3 – Dr. Da Pozzo L et Al.
(Studio multricentrico in cinque Univ.: S.Raffaele – Mi, Federico II NA, Careggi FI, S.Orsola-Malpighi BO, Cattinara Trieste)

188

80

51

44

84

60

Tissue-resonance interaction method for the non-invasive diagnosis of prostate cancer: analysis of a multicentre clinical evaluation
(BJU Int, Nov. 2007)

4 - Prof. Tubaro A et Al.

(HSAndrea – Univ.Roma)

111

86

63

60

88

72

The electromagnetic detection of prostatic cancer: evaluation of diagnostic accuracy

(Urology, Aug. 2008)

5 - Dr Gokce O et Al.

(Dip. Urologia –Univ. Istanbul)

148

76

61

40

89

 

TRIMprob has the potential to be used alongside the recognized tests in the screening protocols for prostate cancer
(Int J Urol, Jun. 2009)

6 - Prof. Cerulli, dr.Di Viccaro et Al (Univ.Umberto I° Roma)

782

(with
PSA>
4ng/ml)

84,1

(with
PSA>
4ng/ml)

67,8

(with PSA>
4ng/ml)

61,7

(with PSA>
4ng/ml)


83,8

 

The accuracy of tissue resonance interaction method probe (Trimprob tm) in non-invasive diagnosis of prostatic cancer. Analysis of the result of 782 patients (Urologia 2009)

BLADDER

             

7 - Dr. Leucci, Prof Vedruccio
(H. Vito Fazzi – Lecce)

114

87,5
(Cohen’s K = 0.77)

90,5
(P < 0.001)

 

83,3

91,1

89,5

Diagnosis of bladder cancer at 465 MHz.
(Electromagn Biol Med, 2007)

7.1 - Prof. Cormio et Al.

125

97,9

89,9

86,8

98,6

93,6

"Non-Invasive Electromagnetic Detection of Bladder Cancer," ISRN Urology, vol. 2014, Article ID 802328, 4 pages, 2014. doi:10.1155/2014/802328. Link

BREAST

             

8 - Dr. Paganelli, dr. De Cicco C(I.E.O. – Milano)

9 - Dr. Carrozza, Prof.Vedruccio(Oncologia Medica Ospedale Umberto I, Lugo - Ravenna)

101

 

180

84

 

 

75

 

(p<0.001)
0,90/0,97

 

80

 

 

 

72

 

 

 

Clinical application of spectral electromagnetic interaction in breast cancer: diagnostic results of a pilot study(Tumori, 2006)

Breast Cancer Diagnosis Possibility By Means Of Vedruccio’s Non-Linear Resonance Interaction Scanner (TRIMprob) (2007)

TYROID

             

10 - Prof. Sacco R et Al.
(Clinica Chir. –Univ Catanzaro)

51

100

100

   

100

Preoperative diagnosis of incidental carcinoma in multinodular goitre by means of electromagnetic interactions
(Chir Ital, Apr. 2007)

STOMACH - DUODENUM

             

11 - Prof Vedruccio C/ Prof. Mascia E et Al
(Clinica Chir. Osp MM- Taranto)

 

45

93

93

95

92

 

Ultra high frequency and microwave non-linear interaction …
(Inter Rev Armed Forces Med Services 2005)

12 - Prof. Sacco R et Al.

(Clinica Chir. – Univ Catanzaro)

43

100

100

   

100

Relief of gastric cancer with an electromagnetic interaction system (TRIMprob) in outpatients (Chir Ital, Dec. 2007)

RECTUM

             

13 - Prof. Leo, dr. Vannelli A et Al. (INT – Milano)
Risultati preliminari (2009)

 

14 - Risultati completi (2010)

 

228

 

442

94

 

94

 

85

 

84

 

86

 

92

93

 

88

89

 

90

Diagnosis of rectal cancer by electromagnetic interactions: preliminary results (Dis Colon Rectum, Jan 2009)

 

Diagnosis of rectal cancer by Tissue Resonance Interaction Method, BMC Gastroenterology 2010, 10:45

COLON

             

15 - Dr. Marcello Tufano, dr. Dore et Al. (Univ. Sassari)

121

100

100

   

100

 

C.Vedruccio-C.Ricci, Non invasive radiofrequency diagnostics of cancer. The Bioscanner-Trimprob technology and clinical applications, Journal of Physics: Conferences Series 329 (2011) 012038

16 - Dr. Marcello Tufano, dr. Dore et Al. (Univ. Sassari)

305

99

91

92

99

100

 

ACCURACY OF DIAGNOSTIC BIOSCANNER TRIMprob, NON INVASIVE METHODS IN SEARCH OF THE COLON PRE-CANCEROUS LESIONS. DOUBLE BLIND-STUDY (publication in progress)

 

Tot. 3.784

         

 

Link per la visualizzazione degli articoli scientifici:

1 - Nuove possibilità diagnostiche tramite onde elettromagnetiche (Fisica in medicina 2004)

http://www.clarbrunovedruccio.it/doc/Fisica%20in%20Medicina%202004.pdf

2 - Non-invasive detection of prostate cancer by electromagnetic interaction (European Urology, Jan. 2005)

http://www.ncbi.nlm.nih.gov/pubmed/15582246

3 - Tissue-resonance interaction method for the non-invasive diagnosis of prostate cancer: analysis of a multicentre clinical evaluation (BJU Int, Nov. 2007) http://www.ncbi.nlm.nih.gov/pubmed/17711511

4 - The electromagnetic detection of prostatic cancer: evaluation of diagnostic accuracy (Urology, Aug. 2008)

http://www.ncbi.nlm.nih.gov/pubmed/18336888

5 - TRIMprob has the potential to be used alongside the recognized tests in the screening protocols for prostate cancer (Int J Urol, Jun. 2009) http://www.ncbi.nlm.nih.gov/pubmed/19456986

6 - The accuracy of tissue resonance interaction method probe (Trimprob tm) in non-invasive diagnosis of prostatic cancer. Analysis of the result of 782 patients (Urologia 2009)

http://www.ncbi.nlm.nih.gov/pubmed/21104675

7 - Diagnosis of bladder cancer at 465 MHz. (Electromagn Biol Med, 2007)

http://www.ncbi.nlm.nih.gov/pubmed/17613039

8 - Clinical application of spectral electromagnetic interaction in breast cancer: diagnostic results of a pilot study (Tumori, 2006)

http://www.ncbi.nlm.nih.gov/pubmed/16869237

9 - Breast Cancer Diagnosis Possibility By Means Of Vedruccio’s Non-Linear Resonance Interaction Scanner (TRIMprob) (2007)

http://www.icems.eu/docs/venice/6th_Workshop_Carrozza.pdf

10 - Preoperative diagnosis of incidental carcinoma in multinodular goitre by means of electromagnetic interactions (Chir Ital, Apr. 2007)

http://www.ncbi.nlm.nih.gov/pubmed/17500182

11 - Ultra high frequency and microwave non-linear interaction … (Inter Rev Armed Forces Med Services 2005)

12 - Relief of gastric cancer with an electromagnetic interaction system (TRIMprob) in outpatients (Chir Ital, Dec. 2007)

http://www.ncbi.nlm.nih.gov/pubmed/18360987

13 - Diagnosis of rectal cancer by electromagnetic interactions: preliminary results (Dis Colon Rectum, Jan 2009)

http://www.ncbi.nlm.nih.gov/pubmed/19273973

14 - Diagnosis of rectal cancer by Tissue Resonance Interaction Method, BMC Gastroenterology 2010, 10:45

http://www.biomedcentral.com/1471-230X/10/45

15 - C.Vedruccio-C.Ricci, Non invasive radiofrequency diagnostics of cancer. The Bioscanner-Trimprob technology and clinical applications, Journal of Physics: Conferences Series 329 (2011) 012038

http://iopscience.iop.org/1742-6596/329/1/012038

16 - ACCURACY OF DIAGNOSTIC BIOSCANNER TRIMprob, NON INVASIVE METHODS IN SEARCH OF THE COLON PRE-CANCEROUS LESIONS. DOUBLE BLIND-STUDY http://www.clarbrunovedruccio.it/doc/Poster%20dr%20Tufano%202012%20lesioni%20precanc%20Colon.pdf

 

 

COMPARATIVE TEST STUDY WITH BIOSCANNER TRIMprob AND OTHER PARAMETERS DIAGNOSTIC INDIVIDUALS OR ASSOCIATED

Andrea Tubaro, Cosimo De Nunzio, Alberto Trucchi,Antonella Stoppacciaro e Lucio Miano, The Electromagnetic Detection of Prostatic Cancer: Evaluation of Diagnostic accuracy, Urology 72(2)340-4. (Link)

PARAMETERS SENS SPEC PPV
NPV
ACC
INDIVIDUAL PARAMETERS          
TRIMROB 86 63 60 88 72
PSA TOT 90 16 41 73 45
FREE/TOT 78 34 35 72 50
DRE 40 88 69 69 69
TRUS 36 79 69 48 55
COIN TOSS

 

45 54 36 63 55
           
Associated parameters          
TRIMPROB + DRE 96 57 59 95 72
PSA TOT + DRE 96 13 42 82 46
FREE/TOT PSA + DRE 81 53 51 82 64

 

SENS: sensibility (measures the proportion of actual positives which are correctly identified as such (e.g. the percentage of sick people who are correctly identified as having the condition));

SPEC: specificity (measures the proportion of negatives which are correctly identified as such (e.g. the percentage of healthy people who are correctly identified as not having the condition);

P.P.V. Positive Predictive Value (It is the percentage of patients with a positive test who actually have the disease);   N.P.V. Negative Predictive Value (it is the percentage of patients with a negative test who do not have the disease); ACC: accuracy (correct diagnoses percentage).

DRE: digital rectal examination; TRUS: transrectal ultrasaund.